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Overview

HYALUP+ filler combines the firm particles of
Bi-Phasic with the adhesiveness of Mono-Phasic,
achieving optimal elasticity and cohesion.

With high cohesion and optimized elasticity,
the filler resists deformation in the body, providing
excellent molding effects and retention during integration.

While typical Bi-Phasic fillers have larger particle
sizes, making injection difficult, HYALUP+ has optimized
the purification process to maintain an appropriate
viscosity during injection, ensuring smooth and easy
procedures.

Features

Superior Physical Properties (Optimization of Elasticity and Cohesion)

HYALUP+ filler combines the firm particles of
Bi-Phasic with the adhesiveness of Mono-Phasic,
achieving optimal elasticity and cohesion.

With high cohesion and optimized elasticity,
the filler resists deformation in the body, providing
excellent molding effects and retention during integration.

While typical Bi-Phasic fillers have larger particle
sizes, making injection difficult, HYALUP+ has optimized
the purification process to maintain an appropriate
viscosity during injection, ensuring smooth and easy
procedures.

High Elasticity & Long-Lasting Effect

HYALUP+ is a filler with high elasticity and cohesion,
maintaining its shape for an extended period after
injection while providing a natural volumizing effect.

Its excellent viscoelasticity prevents excessive spreading
within the skin, ensuring a stable and uniform structure.

With a high storage modulus (G’), it integrates stably with
in the body and retains volume for a prolonged duration.

Optimized BDDE and advanced purification technology
slow down the degradation process, ensuring long-lasting
effectiveness in the body.

High-Efficiency Purification System (CCP Technology Applied)

HYALUP+ is a filler that maximizes purification efficiency
through the CCP (Crystal Cube Process) technology.

During the purification process, a uniform cube-shaped
structure is formed, ensuring a consistent cross-section.

This enhances the uniformity of filler particles, providing
a stable volumizing effect within the tissue.

Compared to conventional multi-week purification
processes, the CCP system completes purification within
just 5 days, significantly improving efficiency.

An automated system has been implemented to enhance
process consistency and maintain product uniformity.

By combining membrane dialysis purification with the
CCP process, BDDE residue is minimized.

A longer purification time increases the safety of the filler
and enhances the removal of impurities, ensuring
a high level of purity.

Stable Crosslinking Process (Optimized BDDE Technology)

HYALUP+ filler optimizes the BDDE crosslinking process
to maximize both safety and longevity.

The BDDE crosslinking reaction is conducted under
precisely controlled temperature and time conditions,
minimizing unnecessary crosslinking while maintaining
the filler’s quality.

This ensures that the filler remains naturally stable within
the body while delivering long-lasting effects.

Additionally, the process is designed to minimize HA molecular
modification that may occur during BDDE crosslinking,
preserving the filler’s elasticity and cohesion for optimal
performance.

SPEC

Use Guide

● HYALUP+ 1UP
Superficial Fine Wrinkle

● HYALUP+ 2UP
Frown lines, Crow’s feet,
(Nasolabial folds)

● HYALUP+ 3UP
Deep Volume, Forehead